Which high-risk patient groups should receive influenza antiviral therapy?

Updated: Oct 13, 2021
  • Author: Christian E Sandrock, MD, MPH, FCCP; Chief Editor: Michael Stuart Bronze, MD  more...
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Certain populations are at higher risk for complications from influenza, as a result, initiation of antiviral treatment is recommended as early as possible for suspected or confirmed influenza in the following patient populations:

  • Patients with severe, complicated, or progressive illness
  • Children < 2 years
  • Adults ≥65 years
  • Immunosuppressed patients
  • Pregnant women or women who are 2 weeks postpartum
  • Individuals < 19 years on long-term aspirin therapy
  • American Indians/Alaska Natives
  • Morbidly obese individuals (BMI of ≥40)
  • Residents of nursing homes or other long-term care facilities
  • Patients with certain chronic diseases such as chronic pulmonary (eg, asthma), cardiovascular (excluding hypertension), renal, hepatic, hematological (eg, sickle cell disease), or metabolic disorders (eg, diabetes mellitus), neurological disorders of the brain (eg, stroke), spinal cord, or peripheral nerves, muscular disorders (eg, cerebral palsy, muscular dystrophy), seizure disorders (eg, epilepsy), and patients with intellectual disability or moderate to severe developmental delay

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