What is the dosage of peramivir (Rapivab) for the treatment of influenza?

Updated: Jan 29, 2019
  • Author: Christian E Sandrock, MD, MPH, FCCP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

Infuse diluted IV over 15-30 minutes

Adolescents and adults

  • Aged >13 years: 600 mg IV as a single dose
  • CrCl 30-49 mL/min: 200 mg IV
  • CrCl 10-29 mL/min: 100 mg IV

Children aged 2-12 years

  • 12 mg/kg IV as a single dose; not to exceed 600 mg/dose
  • CrCl 30-49 mL/min: 4 mg/kg IV
  • CrCl 10-29 mL/min: 2 mg/kg IV

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