Which medications in the drug class Antineoplastics, Antimetabolite are used in the treatment of Cutaneous Squamous Cell Carcinoma?

Updated: Jul 08, 2020
  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Antineoplastics, Antimetabolite

Antimetabolite therapy may be used as part of combination therapy in patients with SCC.

Methotrexate (Trexall)

Methotrexate is an antimetabolite that inhibits dihydrofolate reductase, thereby hindering DNA synthesis and cell reproduction in malignant cells. It has been used in combination with other chemotherapeutic agents for the treatment of cancers of the head and neck.

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