What are potential complications of surgical excision for cutaneous squamous cell carcinoma (cSCC)?

Updated: Jul 08, 2020
  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Complications of excision include hematoma, seroma, infection, and wound dehiscence. Furthermore, histologic margins can be reported as negative when they are, in fact, positive (false negative), because the traditional bread-loaf method of tissue sectioning typically results in evaluation of less than 1% of the specimen’s margins. For this reason, cure rates for cSCC following excision do not significantly differ from cure rates following ED&C and may even be somewhat lower.


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