What are potential complications of surgical excision for cutaneous squamous cell carcinoma (cSCC)?

Updated: Jul 08, 2020
  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Complications of excision include hematoma, seroma, infection, and wound dehiscence. Furthermore, histologic margins can be reported as negative when they are, in fact, positive (false negative), because the traditional bread-loaf method of tissue sectioning typically results in evaluation of less than 1% of the specimen’s margins. For this reason, cure rates for cSCC following excision do not significantly differ from cure rates following ED&C and may even be somewhat lower.

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