What is the prevalence of cutaneous squamous cell carcinoma (cSCC)?

Updated: Jul 08, 2020
  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Skin cancers are the most frequently diagnosed cancers in the United States. Determining the number of cSCCs is difficult, however, because reporting of these cases to cancer registries is not required. One report estimated that in 2012, there were over 5.4 million nonmelanoma skin cancers in the United States, with more than 3.3 million people treated. [22] In comparison, the American Cancer Society estimated that almost 1.7 million cases of most other cancers would be diagnosed in the United States in 2017. (Cases of carcinoma in situ located at any site except the urinary bladder were also not included in the figure.) [23]

Of nonmelanoma skin cancers, approximately 80% are basal cell carcinoma (BCC) and 20% are squamous cell carcinoma (SCC). Thus, cSCC is the second most common skin cancer and one of the most common cancers overall in the United States.

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