Which markers for ultraviolet radiation (UVR) vulnerability increase the risk of cutaneous squamous cell carcinoma (cSCC)?

Updated: Jul 08, 2020
  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Host responses that influence cSCC development include genetic predisposition to DNA damage and, in particular, susceptibility to UVR damage. Well-known markers for UVR vulnerability include the following:

  • Fair skin (or a history of repeated sun exposure)

  • Albinism


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