What are the risk factors for cutaneous squamous cell carcinoma (cSCC)?

Updated: Jul 08, 2020
  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Exposure to cancer-promoting stressors and the response of the body to those exposures (host response) promote the development of cSCC. Well-known risk factors include the following:

  • UVR exposure

  • Immunosuppression

  • Exposure to ionizing radiation or chemical carcinogens

  • Human papillomavirus (HPV) infection


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