What are the advantages of deep brain stimulation (DBS) for the treatment of Parkinson Disease (PD)?

Updated: Dec 09, 2020
  • Author: Konstantin V Slavin, MD; Chief Editor: Brian H Kopell, MD  more...
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Answer

Answer

DBS is a minimally invasive surgical procedure. Importanly, it is effective for treatment of patients with PD. The main advantages of DBS are its reversibility and adjustability. DBS leads are placed in the target(s) and allow stimulation parameters to be adjusted in response to changes in the patient’s condition. If DBS induces unwanted adverse effects, the stimulator can be turned off, adjusted, or removed. If DBS proves clinically ineffective, the patient has not suffered an irreversible lesion to the brain.

Additional advantages include the ability to intervene at targets that cannot or should not be treated with neuroablative lesion surgery and the provision of a unique opportunity to study human basal ganglia physiology.


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