Which medications are used in during the performance of sleep endoscopy?

Updated: Aug 21, 2019
  • Author: Philip E Zapanta, MD, FACS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Medications administered to the patient include the following:

  • Glycopyrrolate 0.2 mg IV x 1 - This must be given in the preoperative suite at least 15 minutes prior to DISE; it will decrease the salivary secretions, allowing optimal viewing during DISE

  • Oxymetazoline nasal spray - Two sprays into both nostrils 15 minutes prior to the procedure; it is best to avoid any topical lidocaine, as this could potentially remove and blunt any natural airway reflexes

  • Propofol infusion - Start 100 μ g/kg/min and titrate to patient’s snoring and OSA.

Try to avoid propofol boluses. Too much propofol will lead to a central apneic episode, making it difficult to distinguish between OSA and central apnea in the patient. This concern must be communicated with the anesthesiologist.

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