What causes upper gastrointestinal (GI) bleeding in infants?

Updated: Dec 19, 2018
  • Author: Wayne Wolfram, MD, MPH; Chief Editor: Robert K Minkes, MD, PhD  more...
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Peptic esophagitis caused by gastroesophageal reflux (GER) is a common cause of bleeding in this age group.

Gastritis is primary or secondary in etiology. Primary gastritis is associated with Helicobacter pylori infection and is the most common cause of gastritis in children. Other causes of primary gastritis include steroidal and nonsteroidal anti-inflammatory drug (NSAID) use, Zollinger-Ellison syndrome, and Crohn disease.

Secondary gastritis occurs in association with severe systemic illnesses that result in mucosal ischemia and produce diffuse erosive and hemorrhagic gastric mucosa.

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