What should be considered in patients with intestinal perforation who have not improved following surgery?

Updated: Jul 24, 2020
  • Author: Samy A Azer, MD, PhD, MPH; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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If no obvious improvement in the patient's condition occurs within 2-3 days, consider the following possibilities:

  • The initial operative procedure was inadequate.
  • Complications have occurred.
  • A superinfection has occurred at a new site.
  • The dose of antibiotic is inadequate.
  • The antibiotics used do not provide adequate coverage for anaerobes and gram-negative organisms.

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