What are the histologic characteristics of mucinous (colloid) carcinoma of the breast?

Updated: May 24, 2018
  • Author: Peter Abdelmessieh, DO, MSc; Chief Editor: Marie Catherine Lee, MD, FACS  more...
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Answer

Answer

Mucin production is the histologic hallmark. Two main forms occur, type A and B, with AB lesions possessing features of both. Type A mucinous carcinoma represents the classic variety with larger quantities of extracellular mucin (see the image below), whereas type B is a distinct variant with endocrine differentiation, with histology showing more granular cytoplasm then type A carcinomas. [5]

Breast cancer. Colloid (mucinous) carcinoma. Nests Breast cancer. Colloid (mucinous) carcinoma. Nests of tumor cells in pool of extracellular mucin

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