Which CSF analysis findings are characteristic of cytomegalovirus ventriculoencephalitis in patients with HIV infection?

Updated: Aug 24, 2017
  • Author: Gulshan Uppal, MD; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Answer

The following CSF characteristics are seen with this condition:

  • Polymorphonuclear pleocytosis (common)

  • Low to normal glucose level

  • Normal to high protein levels

Polymerase chain reaction (PCR) is more sensitive than culture in detecting CMV. In 2 studies, PCR had essentially 100% sensitivity in histologically proven CMV and was positive in 4 samples that had negative culture results.


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