What is the role of CSF analysis in the workup of HIV-associated meningitis?

Updated: Aug 24, 2017
  • Author: Gulshan Uppal, MD; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Answer

CSF analysis facilitates the diagnosis of specific HIV-related etiologies and the assessment of other non–HIV-associated causes. CSF findings include the following:

  • Meningitis at seroconversion and cryptogenic meningitis

  • Cytomegalovirus (CMV) ventriculoencephalitis

  • Cryptococcal meningitis

Sometimes, Cryptococcus neoformans is incidentally found in the CSF.

An asymptomatic form of meningitis is found in one third of patients in whom CSF is examined for other reasons (eg, headache).


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