How does the prevalence of torsade de pointes vary by sex and race?

Updated: Jan 31, 2017
  • Author: Jatin Dave, MD, MPH; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

Answer

For both sexes, the corrected QT interval is longer in white persons than in black persons, possibly explaining the lower susceptibility to acquired torsade in black persons. Brugada syndrome is more frequent in Southeast Asians. [14]

Torsade is 2-3 times more common in women than in men. Women have longer QT intervals, [15] as well as have more QT prolongation secondary to drug therapy. Congenital long QT syndrome is autosomal in genetic transmission but shows a greater frequency of expression and a greater lengthening of the QT interval in women than in men.


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