What are the ASCO guidelines for the use of sentinel lymph node biopsy (SLNB) in the treatment of breast cancer?

Updated: Feb 04, 2021
  • Author: Pavani Chalasani, MD, MPH; Chief Editor: John V Kiluk, MD, FACS  more...
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A 2016 update on SLNB for patients with operable early-stage breast cancer by ASCO advises that SLNB may be offered to the following patients [179] :

  • Women with multicentric tumors
  • Women with DCIS who will be undergoing mastectomy
  • Women who previously underwent breast and/or axillary surgery
  • Women who received preoperative/neoadjuvant systemic therapy

According to the ASCO guidelines, SLNB should not be performed in patients with any of the following:

  • Large or locally advanced invasive breast cancer (tumor size T3/T4)
  • Inflammatory breast cancer
  • DCIS (when breast-conserving surgery is planned)
  • Pregnancy

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