According to ASCO guidelines, which patients with breast cancer should be offered sentinel lymph node (SLN) biopsy?

Updated: Feb 04, 2021
  • Author: Pavani Chalasani, MD, MPH; Chief Editor: John V Kiluk, MD, FACS  more...
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Evaluation of lymph node involvement by means of sentinel lymph node biopsy or axillary lymph node dissection (ALND) has also been considered necessary for staging and prognosis.

A 2014 update on sentinel lymph node biopsy for patients with early-stage breast cancer by the American Society of Clinical Oncology (ASCO) advises that sentinel lymph node biopsy may be offered to the following patients [108] :

  • Women with operable breast cancer and multicentric tumors

  • Women with DCIS who will be undergoing mastectomy

  • Women who previously underwent breast and/or axillary surgery

  • Women who received preoperative/neoadjuvant systemic therapy

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