What is the prognosis of metaplastic breast cancer?

Updated: Dec 27, 2019
  • Author: Pavani Chalasani, MD, MPH; Chief Editor: John V Kiluk, MD, FACS  more...
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Answer

For metaplastic breast cancer, the majority of published case series have demonstrated a worse prognosis than with infiltrating ductal carcinoma, even when adjusted for stage, with a 3-year overall survival rate of 48-71% and 3-year disease-free survival rate of 15-60%. [80] In most case series, large tumor size and advanced stage have emerged as predictors of poor overall survival and prognosis. [81] Nodal status does not appear to impact survival in metaplastic breast cancer.


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