What is the role of combination chemotherapy regimens in the adjuvant therapy for breast cancer?

Updated: May 21, 2019
  • Author: Erin V Newton, MD; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

Answer

Combination regimens

Combination chemotherapy regimens are standard recommendations in the adjuvant setting. Major Cancer and Leukemia Group B (CALGB) chemotherapy clinical trials have consistently shown that chemotherapy produces significantly better disease-free and overall survival, particularly in patients with ER-negative disease.


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