What is the role of lab studies in the diagnosis of psoriasis?

Updated: Mar 17, 2021
  • Author: Jacquiline Habashy, DO, MSc; Chief Editor: William D James, MD  more...
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Laboratory studies and findings for patients with psoriasis may include the following:

  • Test result for rheumatoid factor (RF) is negative.

  • Erythrocyte sedimentation rate (ESR) is usually normal (except in pustular and erythrodermic psoriasis).

  • Uric acid level may be elevated in psoriasis (especially in pustular psoriasis), causing confusion with gout in psoriatic arthritis.

  • Fluid from pustules is sterile with neutrophilic infiltrate.

  • Perform fungal studies. (This is especially important in cases of hand and foot psoriasis that seem to be worsening with the use of topical steroids.)

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