What wound care treatments are under investigation?

Updated: Apr 24, 2020
  • Author: Brian J Daley, MD, MBA, FACS, FCCP, CNSC; Chief Editor: Zubin J Panthaki, MD, CM, FACS, FRCSC  more...
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The aging of the population and advances in biotechnology continue to drive the wound care industry, estimated at $10 billion globally. Besides the always-improving synthetic dressing materials, newer technologies in wound treatment include the xenogeneic tissue scaffold, bilayered human dermal substitutes, recombinant growth factors, endoscopic subfascial ligation of venous perforators, and endovascular arterial repair techniques. The use of hyperbaric oxygen therapy and electrical stimulation remain controversial.

Recent systematic reviews, although not conclusive, suggest that different debridement methods, whether they be chemical, surgical or autolytic, all result in similar results. [65] Other reviews suggest that there may be a role for negative-pressure wound therapy and hyperbaric oxygen in the management of chronic wounds and that there probably is no role for electromagnetic therapy or low-frequency ultrasound therapy based on current best evidence. [66, 67, 68, 69]

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