What are the survival rates following the surgery for thymoma?

Updated: Jul 27, 2020
  • Author: Kendrix J Evans, MD, MS; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Answer

In a retrospective review of 241 patients with thymoma who received radiation therapy after total thymectomy, partial resection, debulking, or biopsy, Wu et al reported 10-year survival rates of 87% for stage I thymoma, 78.7% for stage II, 57.4% for stage III disease, and 24.3% for stage IV. [21] They concluded that surgery and postoperative radiotherapy should be standard for stage II or III but that further research was needed to establish whether this is true for stage I. They also found that the following tended to have a more favorable prognosis:

  • Female patients
  • Patients with early-stage thymoma
  • Patients who underwent surgical extirpation of the neoplasm

A database analysis by Jackson et al found that postoperative radiotherapy was associated with longer overall survival in patients with stage IIB thymoma, but no significant effect could be demonstrated for stage IIA disease. [22]  


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