What is the efficacy of octreotide in the treatment of thymoma?

Updated: Dec 03, 2018
  • Author: Kendrix J Evans, MD, MS; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Answer

Octreotide (0.5 mg SC q8hr) alone or with prednisone (0.6 mg/kg/day) was evaluated in 38 patients with advanced thymomas that expressed somatostatin receptors. [13] Of the 38, four (10.5%) had a partial response with octreotide alone. Of the 21 patients who received octreotide plus prednisone, two had complete responses and four had partial responses. Octrotide plus prednisone yielded better progression-free survival than octreotide alone. Octreotide therapy may be a valuable treatment option when chemotherapy is ineffective.

See Thymoma Treatment Protocols for more information.


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