What is the prognosis of splenic infarct?

Updated: Jul 27, 2020
  • Author: Manish Parikh, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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The prognosis for splenic infarction varies according to the underlying disease process responsible for the infarct. Splenectomies for infarction of massively enlarged spleens accompanying hematologic malignancies reportedly are associated with mortalities as high as 35%. At the other end of the spectrum, many infarcts are clinically occult, with no significant long-term sequelae.

Asplenic individuals have an increased lifetime risk for developing overwhelming postsplenectomy sepsis (OPSS), with the highest rate in the pediatric age group. Patients should be counseled to seek medical attention even for seemingly minor infections, because these can progress to fatal bloodstream infection within hours.

These considerations have proved to be the impetus for splenic preservation.

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