What is the role of imaging studies in the workup of obsessive-compulsive disorder (OCD)?

Updated: May 17, 2018
  • Author: William M Greenberg, MD; Chief Editor: David Bienenfeld, MD  more...
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Answer

Functional MRI and PET scanning have shown increases in blood flow and metabolic activity in the orbitofrontal cortex, limbic structures, caudate, and thalamus, with a trend toward right-sided predominance.

In some studies, these areas of overactivity have been shown to normalize following successful treatment with either SSRIs or CBT. [19] These imaging modalities, while of value for research, are not indicated for normal workups.


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