Which histologic findings are characteristic of proctitis and anusitis?

Updated: Mar 27, 2020
  • Author: David E Stein, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Answer

Histologic findings are usually consistent with inflammation. However, detailed histology leading to the etiology is often not possible. Severe inflammation destroys the specific histopathologic findings of other diseases, such as IBD or C difficile infection.

Regarding infectious etiologies, diversion colitis, or radiation proctitis, the inflammatory histology is not pathognomonic. The one exception is cytomegalovirus colitis in patients who are immunocompromised, in which inclusion bodies may be seen.


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