What is the role of lab studies in the workup of postcholecystectomy syndrome (PCS)?

Updated: Nov 28, 2018
  • Author: Steen W Jensen, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Initial laboratory studies in the workup for postcholecystectomy syndrome (PCS) usually include the following:

  • Complete blood count (CBC) to screen for infectious etiologies
  • Basic metabolic panel (BMP) and amylase level to screen for pancreatic disease
  • Hepatic function panel (HFP) and prothrombin time (PT) to screen for possible liver or biliary tract diseases
  • If the patient is acutely ill, blood gas analysis

If laboratory findings are within reference ranges, consideration should be given to repeating these studies when symptoms are present.

Other laboratory studies that may be indicated are as follows:

  • Lipase
  • Gamma-glutamyl transpeptidase (GGT)
  • Hepatitis panel
  • Thyroid function
  • Cardiac enzymes

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