What are the KDIGO criteria of acute kidney injury (AKI)?

Updated: Aug 07, 2018
  • Author: Piper Julie Hughes, MD, MS; Chief Editor: Vecihi Batuman, MD, FASN  more...
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In 2012 the Kidney Disease Improving Global Outcomes (KDIGO) released their clinical practice guidelines for acute kidney injury (AKI), which build off of the RIFLE criteria and the AKIN criteria. [11]

KDIGO defines AKI as any of the following:

  • Increase in serum creatinine by 0.3mg/dL or more within 48 hours or

  • Increase in serum creatinine to 1.5 times baseline or more within the last 7 days or

  • Urine output less than 0.5 mL/kg/h for 6 hours

The KDIGO has also recommended a staging system for the severity of the AKI.

The KDIGO consensus classification has yet to be validated.

Table 2. KDIGO Staging for AKI Severity (Open Table in a new window)


Serum Creatinine

Urine Output


1.5-1.9 times baseline


≥0.3 mg/dL increase

< 0.5 mL/kg/h for 6 h


2-2.9 times baseline

< 0.5 mL/kg/h for 12 h


3 times baseline


Increase in serum creatinine to ≥4 mg/dL


Initiation of renal replacement therapy

< 0.3 mL/kg/h for 24 h


Anuria for ≥12 h

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