What are the KDIGO criteria of acute kidney injury (AKI)?

Updated: Aug 07, 2018
  • Author: Piper Julie Hughes, MD, MS; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Answer

In 2012 the Kidney Disease Improving Global Outcomes (KDIGO) released their clinical practice guidelines for acute kidney injury (AKI), which build off of the RIFLE criteria and the AKIN criteria. [11]

KDIGO defines AKI as any of the following:

  • Increase in serum creatinine by 0.3mg/dL or more within 48 hours or

  • Increase in serum creatinine to 1.5 times baseline or more within the last 7 days or

  • Urine output less than 0.5 mL/kg/h for 6 hours

The KDIGO has also recommended a staging system for the severity of the AKI.

The KDIGO consensus classification has yet to be validated.

Table 2. KDIGO Staging for AKI Severity (Open Table in a new window)

Stage

Serum Creatinine

Urine Output

1

1.5-1.9 times baseline

or

≥0.3 mg/dL increase

< 0.5 mL/kg/h for 6 h

2

2-2.9 times baseline

< 0.5 mL/kg/h for 12 h

3

3 times baseline

or

Increase in serum creatinine to ≥4 mg/dL

or

Initiation of renal replacement therapy

< 0.3 mL/kg/h for 24 h

or

Anuria for ≥12 h


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