How do the AKIN criteria differ from the RIFLE criteria for acute kidney injury (AKI)?

Updated: Aug 07, 2018
  • Author: Piper Julie Hughes, MD, MS; Chief Editor: Vecihi Batuman, MD, FASN  more...
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The AKIN criteria differ from the RIFLE criteria in several ways. The RIFLE criteria are defined as changes within 7 days, while the AKIN criteria suggest using 48 hours. The AKIN classification includes less severe injury in the criteria and AKIN also avoids using the glomerular filtration rate as a marker in AKI, as there is no dependable way to measure glomerular filtration rate and estimated glomerular filtration rate are unreliable in AKI.

AKIN notes that the diagnostic criteria proposed only after volume status has been optimized and urinary tract obstructions must be excluded when using oliguria as diagnostic criteria.

Fujii and colleagues assessed the three systems discriminative ability based on serum creatinine for the prediction of hospital mortaliy and found the AKIN classification system to be inferior to the RIFLE and KDIGO systems. [10]

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