What are the anterior segment ocular manifestations of sickle cell disease (SCD)?

Updated: Sep 30, 2020
  • Author: Mark Ventocilla, OD, FAAO; Chief Editor: Hampton Roy, Sr, MD  more...
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Answer

Answer

Sickle cell vasoocclusive events can affect every vascular bed in the eye, often with visually devastating consequences in advanced stages of the disease.

Anterior segment abnormalities include the following:

  • Segmentation "corkscrew" conjunctival vessel, more commonly seen in the inferior bulbar conjunctiva

  • Iris infarct and atrophy

  • Cataracts

  • Phthisis bulbi

  • Hyphema


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