What are the anterior segment ocular manifestations of sickle cell disease (SCD)?

Updated: Jul 22, 2021
  • Author: Mark Ventocilla, OD, FAAO; Chief Editor: Andrew G Lee, MD  more...
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Sickle cell vasoocclusive events can affect every vascular bed in the eye, often with visually devastating consequences in advanced stages of the disease.

Anterior segment abnormalities include the following:

  • Segmentation "corkscrew" conjunctival vessel, more commonly seen in the inferior bulbar conjunctiva

  • Iris infarct and atrophy

  • Cataracts

  • Phthisis bulbi

  • Hyphema

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