What is the role of fibrinolytics in the treatment of ischemic stroke and what are possible complications?

Updated: May 27, 2020
  • Author: Edward C Jauch, MD, MS, FAHA, FACEP; Chief Editor: Helmi L Lutsep, MD  more...
  • Print
Answer

Fibrinolytics (ie, rt-PA) restore cerebral blood flow in some patients with acute ischemic stroke and may lead to improvement or resolution of neurologic deficits. Unfortunately, fibrinolytics may also cause symptomatic intracranial hemorrhage. Other complications include potentially extracranial hemorrhage and angioedema or allergic reactions. [1]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!