Which fibrinolytic agent has been shown to benefit patients with acute ischemic stroke (AIS)?

Updated: May 27, 2020
  • Author: Edward C Jauch, MD, MS, FAHA, FACEP; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

The only fibrinolytic agent that has been shown to benefit selected patients with acute ischemic stroke is alteplase (rt-PA). While streptokinase may benefit patients with acute MI, in patients with acute ischemic stroke it has been shown to increase the risk of intracranial hemorrhage and death.


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