Which modifiable factors increase the risk for ischemic stroke?

Updated: May 27, 2020
  • Author: Edward C Jauch, MD, MS, FAHA, FACEP; Chief Editor: Helmi L Lutsep, MD  more...
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Modifiable risk factors include the following [22] :

  • Hypertension (the most important)

  • Diabetes mellitus

  • Cardiac disease: Atrial fibrillation, valvular disease, heart failure, mitral stenosis, structural anomalies allowing right-to-left shunting (eg, patent foramen ovale), and atrial and ventricular enlargement

  • Hypercholesterolemia

  • Transient ischemic attacks (TIA)

  • Carotid stenosis

  • Hyperhomocystinemia

  • Lifestyle issues: Excessive alcohol intake, tobacco use, illicit drug use, physical inactivity [23]

  • Obesity

  • Oral contraceptive use/postmenopausal hormone use

  • Sickle cell disease

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