What are the options for warfarin reversal in patients with hemorrhagic stroke?

Updated: Apr 22, 2019
  • Author: David S Liebeskind, MD, FAAN, FAHA, FANA; Chief Editor: Andrew K Chang, MD, MS  more...
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Answer

The need to reverse warfarin anticoagulation is a true medical emergency, and reversal must be accomplished as quickly as possible to prevent further hematoma expansion. Options for reversal therapy include the following:

  • Intravenous vitamin K

  • Fresh frozen plasma (FFP)

  • Prothrombin complex concentrates (PCC)

  • rFVIIa


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