Which histologic findings are characteristic of lipomas?

Updated: Mar 26, 2020
  • Author: Todd A Nickloes, DO, FACOS; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Answer

Lipomas are benign mesenchymal tumors derived from adipocytes. Several variants have been described, including the following:

  • Adenolipomas, a variation of lipomas that may occur in the breast, often have a marked fibrotic component; they are best regarded as a hamartoma
  • Angiolipomas contain many small vessels
  • Cardiac lipomas may calcify following fat necrosis; microscopically, they are composed of fatty tissue with interlacing muscle fibers

FNA biopsies of a lipoblastoma contain multivacuolated lipoblasts, myxoid areas, and a plexiform capillary network.


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