What is the half-life of heparin and when is the anticoagulant effect of therapeutic doses eliminated in patients with deep venous thrombosis (DVT)?

Updated: Jun 05, 2019
  • Author: Kaushal (Kevin) Patel, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Heparin has a relatively short half-life of about 60–90 minutes and, therefore, the anticoagulant effect of therapeutic doses of heparin will mostly be eliminated at 3-4 hours after termination of continuous intravenous administration


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