What are the exclusion criteria for outpatient treatment of deep venous thrombosis (DVT)?

Updated: Jun 05, 2019
  • Author: Kaushal (Kevin) Patel, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Most patients with confirmed proximal vein DVT may be safely treated on an outpatient basis. Exclusion criteria for outpatient management are as follows:

  • Suspected or proven concomitant PE

  • Significant cardiovascular or pulmonary comorbidity

  • Iliofemoral DVT

  • Contraindications to anticoagulation

  • Familial or inherited disorder of coagulation: antithrombin III (ATIII) deficiency, prothrombin 20210A, protein C or protein S deficiency, or factor V Leiden

  • Familial bleeding disorder

  • Pregnancy

  • Morbid obesity (>150 kg)

  • Renal failure (creatinine >2 mg/dL)

  • Unavailable or unable to arrange close follow-up care

  • Unable to follow instructions

  • Homeless

  • No contact telephone

  • Geographic (too far from hospital)

  • Patient/family resistant to outpatient therapy

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