What are the risk factors for deep venous thrombosis (DVT)?

Updated: Jun 05, 2019
  • Author: Kaushal (Kevin) Patel, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

A summary of risk factors is as follows:

  • Age

  • Immobilization longer than 3 days

  • Pregnancy and the postpartum period

  • Major surgery in previous 4 weeks

  • Long plane or car trips (>4 hours) in previous 4 weeks

  • Cancer

  • Previous DVT

  • Stroke

  • Acute myocardial infarction (AMI)

  • Congestive heart failure (CHF)

  • Sepsis

  • Nephrotic syndrome

  • Ulcerative colitis

  • Multiple trauma

  • CNS/spinal cord injury

  • Burns

  • Lower extremity fractures

  • Systemic lupus erythematosus (SLE) and the lupus anticoagulant

  • Behçet syndrome

  • Homocystinuria

  • Polycythemia rubra vera

  • Thrombocytosis

  • Inherited disorders of coagulation/fibrinolysis

  • Antithrombin III deficiency

  • Protein C deficiency

  • Protein S deficiency

  • Prothrombin 20210A mutation

  • Factor V Leiden

  • Dysfibrinogenemias and disorders of plasminogen activation

  • Intravenous (IV) drug abuse

  • Oral contraceptives

  • Estrogens

  • Heparin-induced thrombocytopenia (HIT)


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