Which factor Xa inhibitors are used in the treatment of deep venous thrombosis (DVT)?

Updated: Jul 05, 2017
  • Author: Kaushal (Kevin) Patel, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Factor Xa inhibitors used in the treatment of DVT include the following:

  • Fondaparinux – This agent appears to be comparable to enoxaparin with respect to efficacy and safety [6]

  • Rivaroxaban – This agent appears to prevent VTE recurrence as effectively as enoxaparin followed by a vitamin K antagonist and may be associated with less bleeding [7, 8, 9] ; in addition, it appears to be usable in high-risk groups


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