Which medications in the drug class Nonsteroidal anti-inflammatory drugs are used in the treatment of Ankle Sprain?

Updated: Jan 14, 2019
  • Author: Craig C Young, MD; Chief Editor: Sherwin SW Ho, MD  more...
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Nonsteroidal anti-inflammatory drugs

If significant ecchymosis is observed at the presentation of acute injury, consider not prescribing for 24-48 h, which may prevent further hemorrhage into the injury site. The NSAIDs listed here are considered first-line drugs on most formularies, but several other agents in this category are available.

Ibuprofen (Motrin, Advil, Nuprin)

Used for analgesia and anti-inflammatory effect; take with food. Member of the propionic acid group of NSAIDs. Available in low-dose form as an over-the-counter medication. Highly protein bound, metabolized in liver, and eliminated primarily in urine. May reversibly inhibit platelet function.

Naproxen (Aleve, Naprelan, Naprosyn, Anaprox)

Used as an analgesic and anti-inflammatory medication; take with food.

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