Which medications in the drug class Skeletal Muscle Relaxants (Direct Acting) are used in the treatment of Pressure Injuries (Pressure Ulcers) and Wound Care?

Updated: Jun 11, 2018
  • Author: Christian N Kirman, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Answer

Skeletal Muscle Relaxants (Direct Acting)

Direct-acting skeletal muscle relaxants inhibit muscle contraction by decreasing calcium release from the sarcoplasmic reticulum in muscle cells.

Dantrolene (Dantrium, Revonto)

Dantrolene stimulates muscle relaxation by modulating the skeletal muscle contractions at a site beyond the myoneural junction and by acting directly on the muscle itself. Most patients respond to a dosage of 400 mg/day or less.


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