What is an algorithmic approach to evaluation of pressure injuries (pressure ulcers)?

Updated: Mar 26, 2020
  • Author: Christian N Kirman, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Evaluation of a patient with an infected wound should follow an algorithmic approach. The following questions should be asked:

  • Is the infection local (rubor, dolor, calor) or systemic (fever, tachycardia, hypotension, delirium, altered mental status)?
  • Which antibiotic is most appropriate for the patient?
  • Does the patient have any known allergies?
  • Does the patient have any metabolic impairments that would alter the pharmacokinetics or pharmacodynamics of the drug?
  • What are the effects of the drug on the hematopoietic system?
  • What attributes does the drug possess for effective tissue penetration (ie, how much of the drug actually ends up in the tissue of interest)?
  • How is the drug metabolized?
  • What are the patient’s total weight and lean body and fat mass?

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