What is the role of bone biopsy in the diagnosis of pressure injuries (pressure ulcers)?

Updated: Mar 26, 2020
  • Author: Christian N Kirman, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Bone biopsy is the criterion standard for the diagnosis of osteomyelitis within a pressure injury. [71] It should be considered in patients with an elevated ESR, an elevated WBC count, and or abnormal pelvic films suggestive of osteomyelitis, as well as in cases of stage 4 pressure injury with exposed bone. If osteomyelitis is confirmed, treatment with a prolonged course of antibiotic therapy may be indicated.

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