What is the role of tissue biopsy in the management of chronic pressure injuries (pressure ulcers)?

Updated: Mar 26, 2020
  • Author: Christian N Kirman, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Tissue biopsy of chronic wounds is indicated to rule out the presence of an underlying malignancy (ie, Marjolin ulceration). Whenever a chronic pressure injury has been stable for months or years but has recently deteriorated, a biopsy should be performed. Scar carcinoma is uncommon and typically occurs in wounds that have been open for many years.

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