What is the role of tissue biopsy in the diagnosis of pressure injuries (pressure ulcers)?

Updated: Mar 26, 2020
  • Author: Christian N Kirman, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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A tissue biopsy should be performed for wounds that do not demonstrate clinical improvement despite adequate care and for wounds in which tissue invasion by bacteria is suggested. This allows quantification and identification of bacterial species and their antibiotic susceptibilities. Biopsy also enables the clinician to distinguish between simple contamination and tissue invasion, an important distinction that is not revealed by the common practice of swabbing the wound surface for culture.

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