Which research questions need to be addressed regarding pressure injuries (pressure ulcers)?

Updated: Mar 26, 2020
  • Author: Christian N Kirman, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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To date, clinical studies of pressure injuries have been difficult to assess because they have often been qualitatively based on random observation and uncontrolled studies. To arrive at more reliable conclusions, more fundamental approaches to these injuries must be considered. Questions that might be asked include the following:

  • What are the basic histologic, pathologic, and biochemical markers in an evolving pressure injury?
  • Is it ethical to take a biopsy specimen of a human pressure injury for purposes of research?
  • What are the multiple variables in the formation of pressure injuries in the human environment?

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