What is the most common cause of intersex differentiation syndrome in girls with abdominal inguinal hernias?

Updated: Jul 23, 2019
  • Author: Assar A Rather, MBBS, MD, FACS; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

The most common cause of this is testicular feminization (androgen insensitivity) syndrome, which results from end-androgen resistance and leads to a small testis and a rudimentary vagina (persistent genitourinary sinus) without fallopian tubes or a uterus. If a girl with a hernia has testicular feminization, a gonadectomy on one side and isolation of the other gonad in a superficial position until puberty permits secondary sexual characteristics to develop. Hermaphrodites have an asymmetric ovotestis, which should not be removed.


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