What are the clinical manifestations of maldevelopment of the lateral fold in abdominal hernias?

Updated: Jul 23, 2019
  • Author: Assar A Rather, MBBS, MD, FACS; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

Lateral fold maldevelopment results in omphalocele (see the image below), as well as gastroschisis. It has been postulated that an omphalocele results from persistence of the umbilical stalk in the somatopleure. Approximately 20% of infants with omphaloceles have an associated chromosomal abnormality (eg, trisomy 13, trisomy 18, trisomy 21, or Klinefelter syndrome).

Note translucent sac in baby with large omphalocel Note translucent sac in baby with large omphalocele. Umbilical vessels attach to sac.

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