What are category III disorders for which the optimal role of plasmapheresis therapy is not established?

Updated: Mar 08, 2021
  • Author: Elliot Stieglitz, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Category III indications (disorders for which the optimal role of apheresis therapy is not established; decision-making should be individualized) include the following:

  • Posttransfusion purpura
  • RBC alloimmunization in pregnancy
  • Autoimmune hemolytic anemia (severe warm)
  • Hypertriglyceridemic pancreatitis [11]
  • Thrombotic microangiopathy, complement mediated (complement factor mutations)
  • Drug overdose/poisoning
  • Immune thrombocytopenia

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