What are the reported outcomes for total mesorectal excision (TME)?

Updated: Feb 16, 2021
  • Author: Nanda Kishore Maroju, MRCS, MS, MBBS, DNB; Chief Editor: Kurt E Roberts, MD  more...
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The circumferential resection margin positivity rate is about 5% or less for low anterior resections with TME, whereas it is between 10% and 25% for abdominoperineal excision of the rectum. There is, understandably, a higher local recurrence rate following abdominoperineal excision of the rectum. The 5-year survival and disease-free survival rates are significantly lower with TME.

Evidence suggests that a circumferential resection margin of 1 mm or less adversely affects cancer-specific survival, local recurrence, and distant metastasis. [2]

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